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https://swslhd.intersearch.com.au/swslhdjspui/handle/1/12732
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DC Field | Value | Language |
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dc.contributor.author | Farrell, R. | - |
dc.contributor.author | Zaunders, J. | - |
dc.contributor.author | Poynten, I. M. | - |
dc.contributor.author | Anderson, L. | - |
dc.contributor.author | Evans, L. | - |
dc.date.accessioned | 2024-06-03T03:25:39Z | - |
dc.date.available | 2024-06-03T03:25:39Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 23525789 (ISSN) | - |
dc.identifier.uri | https://swslhd.intersearch.com.au/swslhdjspui/handle/1/12732 | - |
dc.description.abstract | This is the first report describing detailed T cell responses to viral-like proteins contained in an HPV specific vaccine given in combination with Imiquimod for treatment of persistent VAIN2/3. We postulate that stimulation of the innate immune system with Imiquimod and the specific CD4 and CD8T cell responses following HPV vaccination with Gardasil9@ combined to induce clinical remission in a woman with treatment-refractory disease. � 2024 The Author(s) | - |
dc.publisher | Elsevier B.V. | - |
dc.subject | HPV vaccine Human papillomavirus (HPV) Imiquimod Vaginal intraepitheial neoplasia (VAIN) eosin hematoxylin Human papilloma virus vaccine recombinant protein adult anamnesis anesthesia Article biopsy case report CD4+ T lymphocyte CD8+ T lymphocyte clinical article colposcopy cream cytology disease association excision female flu like syndrome follow up genotyping high-grade vaginal intraepithelial neoplasia human Human papillomavirus type 52 human tissue immune deficiency immunohistochemistry immunologist immunostimulation in vitro study laser therapy nullipara papillomavirus infection patient referral polymerase chain reaction pregnancy recommended drug dose remission treatment duration vaccination vagina vagina bleeding Wart virus | - |
dc.title | Concurrent nonavalent human papillomavirus (HPV) vaccination and immune stimulation with imiquimod to treat recalcitrant HPV-associated high grade vaginal intra-epithelial neoplasia | - |
dc.type | Journal Article | - |
dc.contributor.swslhdauthor | Evans, Louise | - |
dc.description.affiliates | Chris O'Brien Lifehouse Hospital, Camperdown, Sydney, 2050, NSW, Australia Sydney Medical School, University of Sydney, 2006, NSW, Australia NSW State Reference Labaoratory for HIV, Centre for Applied Medical Research, St Vincents Hospital, NSW, Australia HIV Epidemiology and Prevention Program, The Kirby Institute, University of NSW Kensington, Sydney, 2052, NSW, Australia NSW Health Pathology, Royal Prince Alfred Hospital, Camperdown, Sydney, 2050, NSW, Australia University of NSW Kensington, Sydney, 2052, NSW, Australia Department of Clinical Immunology, Allergy and HIV, Liverpool Hospital, South Western Sydney Local Health District, Liverpool Sydney, 2170, NSW, Australia | - |
dc.identifier.doi | 10.1016/j.gore.2024.101350 | - |
dc.identifier.department | Liverpool Hospital, Department of Clinical Immunology, Allergy and HIV | - |
dc.type.studyortrial | Article | - |
dc.identifier.journaltitle | Gynecologic Oncology Reports | - |
Appears in Collections: | Liverpool Hospital South Western Sydney Local Health District |
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