This research determined variables potentially involved in influencing Lidcombe Program treatment time. The method used retrospective case studies of 10 pre-school children with rapid treatment responses and 10 with slow treatment responses. Results were consistent with existing findings that associated pretreatment stuttering severity with longer treatment time. A new suggestion emerged about children whose siblings had been successfully treated; those cases were more likely to be associated...

BACKGROUND: Endoscopic lung volume reduction (ELVR) has been shown to improve lung function, quality of life, and exercise tolerance in patients with severe heterogeneous emphysema. Our study aims to determine the effect of ELVR on gas transfer capacity corrected for alveolar volume (KCO) and investigate the relationship between KCO and ventilation and perfusion (VQ) matching. We speculate on possible mechanisms for the observed changes METHODS

The range of biologic therapies currently available for treating inflammatory bowel disease (IBD) include anti-tumor necrosis factor (anti-TNF) agents, infliximab, adalimumab, certolizumab, and golimumab; one anti-adhesion molecule, vedolizumab; and one interleukin (IL) 12/IL-23 antagonist, ustekinumab. The foundation of selecting the optimal treatment for a patient with IBD rests in individualized assessment of a patient?s risk-to-benefit ratio. � 2022 by Taylor & Francis Group.

Introduction: Local Australian guidelines for the optimal management of stage III unresectable non-small cell lung cancer (NSCLC) are lacking. The American Society of Clinical Oncology (ASCO) guidelines recommend consolidation durvalumab for all patients with unresectable stage III NSCLC, irrespective of their PD-L1 expression or driver mutation status. The European Society of Medical Oncology (ESMO) differs, with consolidation durvalumab only recommended in those patients whose tumours expre...

The development and market emergence of vaginal sensors have begun to demonstrate their impact on women?s healthcare. Until recently, in limited cases, these sensors have exhibited their capabilities in diagnosing and monitoring disorders of the vaginal tract during different stages of women?s lives. This Perspective is a compilation of what has been accomplished so far in the landscape of vaginal sensors. The text explores the diverse types of vaginal sensor technologies, their applications,...

Background: The European Resuscitation Council 2021 guidelines for haemodynamic monitoring and management during post-resuscitation care from cardiac arrest call for an individualised approach to therapeutic interventions. Combining the cardiac function and venous return curves with the inclusion of the mean systemic filling pressure enables a physiological illustration of intravascular volume, vasoconstriction and inotropy. An analogue mean systemic filling pressure (Pmsa) may be calculated ...

The heterogeneity of autism spectrum disorder (ASD) clinically and aetiologically hinders intervention matching and prediction of outcomes. This study investigated if the behavioural, sensory, and perinatal factor profiles of autistic children could be used to identify distinct subgroups. Participants on the autism spectrum aged 2 to 17 years and their families were sourced via the Australian Autism Biobank (AAB). Latent class analysis was used to identify subgroups within this cohort, utilis...

Study objective: We previously designed and validated a virtual reality-based simulator to help train novices in ultrasound-guided needling skills necessary for safe and competent ultrasound-guided regional anaesthesia. This study was designed to compare the performance and error rates of novices trained by a human faculty aided with the assistance of this virtual reality simulator (virtual reality-assisted training), versus novices trained wholly by humans (conventional training). Design, se...

Background: The Sydney Facial Nerve Service is a multidisciplinary team that provides management of patients with facial nerve disorders, historically as an in-person format. The coronavirus disease 2019 (COVID-19) pandemic resulted in a shift to a virtual format due to infection control precautions. This study aims to evaluate the acceptability of a telehealth format for patients and clinicians in the multidisciplinary care of facial nerve palsy. Methods: The questionnaires were distributed ...

Aim: To conduct a child and family health nursing service redesign to improve pathways of access, response and outcomes for all families with children aged 0?5 years. Design: The study was conducted as an iterative, mixed-method study of the process and impact of the service redesign, informed by a participatory action research paradigm and the NSW Agency for Clinical Innovation process for developing a model of care. Methods: Diagnostic, solution design, implementation and sustainability pha...

Purpose: To investigate massage therapists? attitudes, consultation processes, and confidence to respond to situations involving domestic and family violence (DFV) in clinical practice. Methods: An online survey-based study was conducted and Australian massage therapists, 18�years of age or over were recruited. The survey included 64 questions in 3 sections: 1) Demographics, 2) Recognize Family and Domestic Violence, and 3) Respond to domestic and family violence with 4 subsections; i) disclo...

Currently, there are no resources to support culturally and linguistically diverse (CALD) women with breast cancer to make decisions about undergoing breast reconstruction (BR). This study evaluated the usability and acceptability of decision aids (DAs) for Vietnamese- and Arabic-speaking women. This two-phase qualitative recruited Vietnamese- (Phase 1) and Arabic-speaking (Phase 2) adult (age ? 18 years) women who were diagnosed with breast cancer and could read Vietnamese/Arabic. Women part...

Background: Autistic children are prone to experience heightened levels of distress and physiological reactivity to a range of sensory, social, and emotional stimuli. In line with this, multiple studies have demonstrated that autistic children have higher acute cortisol stress responses to adverse or threatening stimuli and altered cortisol awakening responses. However, few studies have examined whether this sensitivity may relate to heightened levels of chronic stress and persistently elevat...

Recurrent hamstring injuries are highly prevalent amongst sporting populations. It has been hypothesised that pain from an initial hamstring injury may induce reorganisation of somatosensory representations that could contribute to reinjury. However, because of the cross-sectional nature of existing research, it remains unknown whether somatosensory changes are a cause or effect of pain or if they are driven by other potentially confounding factors. Here, we explored the effect of experimenta...

OBJECTIVE: To explore how Michel de Montaigne's battle with urolithiasis influenced his writings and philosophical outlook during the Renaissance period. MATERIALS AND METHODS: The study examines historical texts, Montaigne's personal essays, and contemporary medical literature from the Renaissance era. A comprehensive review of Montaigne's extensive travels across Europe, interactions with prominent physicians, and the various treatments he sought for urolithiasis is conducted. The analysis ...