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Title: | Haemophagocytic lymphohistiocytosis secondary to disseminated histoplasmosis in an immunocompetent patient |
Authors: | Morton, M. Vanguru, V. Shin, J. S. Ronnachit, A. |
SWSLHD Author: | Mallory Morton |
Affiliates: | Department of Infectious Diseases, Royal Prince Alfred Hospital, Sydney, 2050, NSW, Australia Department of Medicine, Campbelltown Hospital, Campbelltown, 2560, NSW, Australia Institute of Haematology, Royal Prince Alfred Hospital, Sydney, 2050, NSW, Australia Tissue Pathology and Diagnostic Oncology, Royal Prince Alfred Hospital, Sydney, 2050, NSW, Australia Faculty of Medicine, University of Sydney, Sydney, 2006, NSW, Australia Macfarlane Burnet Institute, Melbourne, 3004, VIC, Australia |
Department: | Campbelltown Hospital, Department of Medicine |
Issue Date: | 2024 |
Journal: | Medical Mycology Case Reports |
Publisher: | Elsevier B.V. |
Abstract: | Haemophagocytic lymphohistiocytosis secondary to Histoplasma infection is rare and almost always occurs in immunocompromised hosts. We report a 32-year-old immunocompetent man presenting with a nonspecific febrile illness found to have disseminated histoplasmosis and associated haemophagocytic lymphohistiocytosis. The diagnosis was confirmed on histopathological examination and PCR of liver and bone marrow biopsies. He was successfully treated with steroids, intravenous immunoglobulin and itraconazole. � 2024 |
URI: | https://swslhd.intersearch.com.au/swslhdjspui/handle/1/12606 |
ISSN: | 22117539 (ISSN) |
Digital object identifier: | 10.1016/j.mmcr.2024.100635 |
Appears in Collections: | Camden and Campbelltown Hospitals |
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